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Phytochemical analysis and anticholinesterase activity of aril of Myristica fragrans Houtt.
Rastegari A, Manayi A, Rezakazemi M, Eftekhari M, Khanavi M, Akbarzadeh T, Saeedi M. Rastegari A, et al. BMC Chem. 2022 Nov 28;16(1):106. doi: 10.1186/s13065-022-00897-9. BMC Chem. 2022. PMID: 36437466 Free PMC article.
The phytochemical study led to isolation and identification of malabaricone A (1), malabaricone C (2), 4-(4-(3,4-dimethoxyphenyl)-2,3-dimethylbutyl)benzene-1,2-diol (3), nectandrin B (4), macelignan (5), and 4-(4-(benzo[d][1,3]dioxol-5-yl)-1-methoxy-2,3-dimethylbutyl)-2-methoxyph …
The phytochemical study led to isolation and identification of malabaricone A (1), malabaricone C (2), 4-(4-(3,4-dimethoxyphenyl)-2,3-dimeth …
Phytochemical investigation and anticholinesterase activity of ethyl acetate fraction of Myristica fragrans Houtt. seeds.
Omidpanah S, Vahedi-Mazdabadi Y, Manayi A, Rastegari A, Hariri R, Mortazavi-Ardestani E, Eftekhari M, Khanavi M, Akbarzadeh T, Saeedi M. Omidpanah S, et al. Nat Prod Res. 2022 Jan;36(2):610-616. doi: 10.1080/14786419.2020.1788555. Epub 2020 Jul 8. Nat Prod Res. 2022. PMID: 32640862
Our results confirmed the presence of trimyristin and 5,7-diacetyl chrysin (reported for the first time in M. fragrans) in the corresponding fraction....
Our results confirmed the presence of trimyristin and 5,7-diacetyl chrysin (reported for the first time in M. fragrans) in the corres …
Cytotoxic evaluation of Melia azedarach in comparison with, Azadirachta indica and its phytochemical investigation.
Jafari S, Saeidnia S, Hajimehdipoor H, Ardekani MR, Faramarzi MA, Hadjiakhoondi A, Khanavi M. Jafari S, et al. Daru. 2013 May 16;21(1):37. doi: 10.1186/2008-2231-21-37. Daru. 2013. PMID: 23679992 Free PMC article.
The study also aimed to determine the active components that are responsible for medicinal effects of M. azedarach in traditional usages. METHODS: In this study, the cytotoxic activity of crude extracts from M. azedarach and A. indica leaves, pulps and seeds as well …
The study also aimed to determine the active components that are responsible for medicinal effects of M. azedarach in traditional usa …
Phytocatalytic and cytotoxic activity of the purified laccase from bled resin of Pistacia atlantica Desf.
ElyasiGhahfarokhi A, Hashemi S, Saeedi M, Khanavi M, Faramarzi MA. ElyasiGhahfarokhi A, et al. Int J Biol Macromol. 2021 Apr 15;176:394-403. doi: 10.1016/j.ijbiomac.2021.01.212. Epub 2021 Feb 3. Int J Biol Macromol. 2021. PMID: 33548319
Moreover, it depicted diphenolase activity and high affinity towards 2,6-dimethoxy phenol (K(m) = 10.01 0.5 mM) and syringaldazine (K(m) = 6.57 0.2 mM) comparing with plant-origin polyphenol oxidases reported in the literature. ...
Moreover, it depicted diphenolase activity and high affinity towards 2,6-dimethoxy phenol (K(m) = 10.01 0.5 mM) and syringaldazine (K …
Design and synthesis of novel coumarin-pyridinium hybrids: In vitro cholinesterase inhibitory activity.
Vafadarnejad F, Mahdavi M, Karimpour-Razkenari E, Edraki N, Sameem B, Khanavi M, Saeedi M, Akbarzadeh T. Vafadarnejad F, et al. Bioorg Chem. 2018 Apr;77:311-319. doi: 10.1016/j.bioorg.2018.01.013. Epub 2018 Jan 31. Bioorg Chem. 2018. PMID: 29421707
Among synthesized compounds, 1-(3-fluorobenzyl)-4-((2-oxo-2H-chromene-3-carboxamido)methyl)pyridinium bromide (7l) was found to be the most active compound toward AChE (IC(50) = 10.14 M), 1-(3-chlorobenzyl)-3-((2-oxo-2H-chromene-3-carboxamido)methyl)pyridinium bromide (7g) …
Among synthesized compounds, 1-(3-fluorobenzyl)-4-((2-oxo-2H-chromene-3-carboxamido)methyl)pyridinium bromide (7l) was found to be the most …
Effects of Melissa officinalis (lemon balm) consumption on serum lipid profile: a meta-analysis of randomized controlled trials.
Shahsavari K, Shams Ardekani MR, Khanavi M, Jamialahmadi T, Iranshahi M, Hasanpour M. Shahsavari K, et al. BMC Complement Med Ther. 2024 Apr 4;24(1):146. doi: 10.1186/s12906-024-04442-0. BMC Complement Med Ther. 2024. PMID: 38575930 Free PMC article.
The present study is the first meta-analysis to investigate the effects of M. officinalis administration on serum levels of high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), triglyceride (TG) and total cholesterol (TC). ...
The present study is the first meta-analysis to investigate the effects of M. officinalis administration on serum levels of high-dens …
Antinociceptive effect of extracts of Marrubium astracanicum Jacq. aerial parts.
Kahkeshani N, Gharedaghi M, Hadjiakhoondi A, Sharifzadeh M, Khanavi M. Kahkeshani N, et al. Avicenna J Phytomed. 2017 Jan-Feb;7(1):73-79. Avicenna J Phytomed. 2017. PMID: 28265549 Free PMC article.
OBJECTIVE: The genus Marrubium is used for treatment of joint pain, gout, stomach-ache and colic in Iranian Traditional Medicine. Marrubium astracanicum Jacq. (M. astracanicum) is a native species in the flora of Iran. The aim of this study was to evaluate the antinocicept …
OBJECTIVE: The genus Marrubium is used for treatment of joint pain, gout, stomach-ache and colic in Iranian Traditional Medicine. Marrubium …